The mediation effects of Interleukin-6 and Cortisol in Hippocampus in relationship beween Interleukin-6 and Cortisol in plasma to effect of psychological stressor on serotonin transporter (SERT) distribution and apoptotic index of hippocampus

Adji Achmad Rinaldo Fernandes

The mediation effects of Interleukin-6 and Cortisol in Hippocampus in relationship beween Interleukin-6 and Cortisol in plasma to effect of psychological stressor on serotonin transporter (SERT) distribution and apoptotic index of hippocampus

Solimun
, Adji Achmad Rinaldo Fernandes^*

^*Corresponding author for this work

Faculty of Mathematics and Natural Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

The aim of this research is to investigate the Mediation Effects of Interleukin-6 and Cortisol in Hippocampus In Relationship beween Interleukin-6 and Cortisol in Plasma to Effect of Psychological Stressor on Serotonin Transporter (SERT) Distribution and Apoptotic Index of Hippocampus. This study uses data Suparno, using a sample of 24 female rats Rattus Wistar novergicus 10-12 weeks of age 150-185 gram weight, which is exposed to predators in the form of two cats who were selected empirically the level of aggressiveness of the rat before and after treatment, then taken blood plasma as well as neuronal networks (pyramidal neurons) hippocampal CA3 area, with a thick slice preparations 2-4 lm. The variables of this research are: independent variables (Interleukin-6 or IL-6 and Cortisol in Plasma), mediation variables (Interleukin-6 and Cortisol in Hippocampus), and dependent variables (SERT and Apoptotic in Hippocampus). The result shows that (1) there is mediation Effects of Interleukin-6 in Hippocampus In Relationship beween Interleukin-6 and Cortisol in Plasma to Effect of Psychological Stressor on Serotonin Transporter (SERT) Distribution and Apoptotic Index of Hippocampus, (2) there is mediation Effects of Cortisol in Hippocampus In Relationship beween Interleukin-6 and Cortisol in Plasma to Effect of Psychological Stressor on Serotonin Transporter (SERT) Distribution and Apoptotic Index of Hippocampus.

Original language	English
Pages (from-to)	491-497
Number of pages	7
Journal	International Journal of ChemTech Research
Volume	9
Issue number	9
Publication status	Published - 2016

Keywords

Apoptotic index
Cortisol
Interleukin-6
Mediation effect
SERT

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Solimun, ; Fernandes, Adji Achmad Rinaldo. / The mediation effects of Interleukin-6 and Cortisol in Hippocampus in relationship beween Interleukin-6 and Cortisol in plasma to effect of psychological stressor on serotonin transporter (SERT) distribution and apoptotic index of hippocampus. In: International Journal of ChemTech Research. 2016 ; Vol. 9, No. 9. pp. 491-497.

@article{c7598fc8d0dd45878f82d798782a2ba8,

title = "The mediation effects of Interleukin-6 and Cortisol in Hippocampus in relationship beween Interleukin-6 and Cortisol in plasma to effect of psychological stressor on serotonin transporter (SERT) distribution and apoptotic index of hippocampus",

abstract = "The aim of this research is to investigate the Mediation Effects of Interleukin-6 and Cortisol in Hippocampus In Relationship beween Interleukin-6 and Cortisol in Plasma to Effect of Psychological Stressor on Serotonin Transporter (SERT) Distribution and Apoptotic Index of Hippocampus. This study uses data Suparno, using a sample of 24 female rats Rattus Wistar novergicus 10-12 weeks of age 150-185 gram weight, which is exposed to predators in the form of two cats who were selected empirically the level of aggressiveness of the rat before and after treatment, then taken blood plasma as well as neuronal networks (pyramidal neurons) hippocampal CA3 area, with a thick slice preparations 2-4 lm. The variables of this research are: independent variables (Interleukin-6 or IL-6 and Cortisol in Plasma), mediation variables (Interleukin-6 and Cortisol in Hippocampus), and dependent variables (SERT and Apoptotic in Hippocampus). The result shows that (1) there is mediation Effects of Interleukin-6 in Hippocampus In Relationship beween Interleukin-6 and Cortisol in Plasma to Effect of Psychological Stressor on Serotonin Transporter (SERT) Distribution and Apoptotic Index of Hippocampus, (2) there is mediation Effects of Cortisol in Hippocampus In Relationship beween Interleukin-6 and Cortisol in Plasma to Effect of Psychological Stressor on Serotonin Transporter (SERT) Distribution and Apoptotic Index of Hippocampus.",

keywords = "Apoptotic index, Cortisol, Interleukin-6, Mediation effect, SERT",

author = "Solimun and Fernandes, \{Adji Achmad Rinaldo\}",

year = "2016",

language = "English",

volume = "9",

pages = "491--497",

journal = "International Journal of ChemTech Research",

issn = "0974-4290",

publisher = "Sphinx Knowledge House",

number = "9",

}

The mediation effects of Interleukin-6 and Cortisol in Hippocampus in relationship beween Interleukin-6 and Cortisol in plasma to effect of psychological stressor on serotonin transporter (SERT) distribution and apoptotic index of hippocampus. / Solimun, ; Fernandes, Adji Achmad Rinaldo.
In: International Journal of ChemTech Research, Vol. 9, No. 9, 2016, p. 491-497.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - The mediation effects of Interleukin-6 and Cortisol in Hippocampus in relationship beween Interleukin-6 and Cortisol in plasma to effect of psychological stressor on serotonin transporter (SERT) distribution and apoptotic index of hippocampus

AU - Solimun,

AU - Fernandes, Adji Achmad Rinaldo

PY - 2016

Y1 - 2016

N2 - The aim of this research is to investigate the Mediation Effects of Interleukin-6 and Cortisol in Hippocampus In Relationship beween Interleukin-6 and Cortisol in Plasma to Effect of Psychological Stressor on Serotonin Transporter (SERT) Distribution and Apoptotic Index of Hippocampus. This study uses data Suparno, using a sample of 24 female rats Rattus Wistar novergicus 10-12 weeks of age 150-185 gram weight, which is exposed to predators in the form of two cats who were selected empirically the level of aggressiveness of the rat before and after treatment, then taken blood plasma as well as neuronal networks (pyramidal neurons) hippocampal CA3 area, with a thick slice preparations 2-4 lm. The variables of this research are: independent variables (Interleukin-6 or IL-6 and Cortisol in Plasma), mediation variables (Interleukin-6 and Cortisol in Hippocampus), and dependent variables (SERT and Apoptotic in Hippocampus). The result shows that (1) there is mediation Effects of Interleukin-6 in Hippocampus In Relationship beween Interleukin-6 and Cortisol in Plasma to Effect of Psychological Stressor on Serotonin Transporter (SERT) Distribution and Apoptotic Index of Hippocampus, (2) there is mediation Effects of Cortisol in Hippocampus In Relationship beween Interleukin-6 and Cortisol in Plasma to Effect of Psychological Stressor on Serotonin Transporter (SERT) Distribution and Apoptotic Index of Hippocampus.

AB - The aim of this research is to investigate the Mediation Effects of Interleukin-6 and Cortisol in Hippocampus In Relationship beween Interleukin-6 and Cortisol in Plasma to Effect of Psychological Stressor on Serotonin Transporter (SERT) Distribution and Apoptotic Index of Hippocampus. This study uses data Suparno, using a sample of 24 female rats Rattus Wistar novergicus 10-12 weeks of age 150-185 gram weight, which is exposed to predators in the form of two cats who were selected empirically the level of aggressiveness of the rat before and after treatment, then taken blood plasma as well as neuronal networks (pyramidal neurons) hippocampal CA3 area, with a thick slice preparations 2-4 lm. The variables of this research are: independent variables (Interleukin-6 or IL-6 and Cortisol in Plasma), mediation variables (Interleukin-6 and Cortisol in Hippocampus), and dependent variables (SERT and Apoptotic in Hippocampus). The result shows that (1) there is mediation Effects of Interleukin-6 in Hippocampus In Relationship beween Interleukin-6 and Cortisol in Plasma to Effect of Psychological Stressor on Serotonin Transporter (SERT) Distribution and Apoptotic Index of Hippocampus, (2) there is mediation Effects of Cortisol in Hippocampus In Relationship beween Interleukin-6 and Cortisol in Plasma to Effect of Psychological Stressor on Serotonin Transporter (SERT) Distribution and Apoptotic Index of Hippocampus.

KW - Apoptotic index

KW - Cortisol

KW - Interleukin-6

KW - Mediation effect

KW - SERT

UR - https://www.scopus.com/pages/publications/84994627687

M3 - Article

AN - SCOPUS:84994627687

SN - 0974-4290

VL - 9

SP - 491

EP - 497

JO - International Journal of ChemTech Research

JF - International Journal of ChemTech Research

IS - 9

ER -

The mediation effects of Interleukin-6 and Cortisol in Hippocampus in relationship beween Interleukin-6 and Cortisol in plasma to effect of psychological stressor on serotonin transporter (SERT) distribution and apoptotic index of hippocampus

Abstract

Keywords

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