The Importance of Natural ACE2 Inhibitor: Potency of Porang (Amorphophallus muelleri) Glucomannan as Anti-SARS-Cov-2

Amira Hasnanuha Ulayya; Ahmad Zaki Mubarok; Widodo Widodo; Simon Bambang Widjanarko; Marlita Marlita

doi:10.29333/ejgm/11402

The Importance of Natural ACE2 Inhibitor: Potency of Porang (Amorphophallus muelleri) Glucomannan as Anti-SARS-Cov-2

Amira Hasnanuha Ulayya^*
, Ahmad Zaki Mubarok
, Widodo Widodo^*
, Simon Bambang Widjanarko
, Marlita Marlita

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

The inhibition of SARS-Cov-2 S binding with hACE2, expressed in most human tissues, may prevent the severity of virus infection. However, commercial ACE2 inhibitor drugs are still limited, while several natural compounds have already been reported to have anti-ACE2 activity. We found the potential of hydrolyzed glucomannan of porang tuber in the inhabitation of binding activity between ACE2 and S1 of SARS-Cov-2.

Original language	English
Article number	em340
Journal	Electronic Journal of General Medicine
Volume	19
Issue number	1
DOIs	https://doi.org/10.29333/ejgm/11402
Publication status	Published - Feb 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

ACE2
Glucomannan
Porang
S1
SARS-Cov-2

Access to Document

10.29333/ejgm/11402

Cite this

@article{1cfd3835c75a4473b184a346c5d81b03,

title = "The Importance of Natural ACE2 Inhibitor: Potency of Porang (Amorphophallus muelleri) Glucomannan as Anti-SARS-Cov-2",

abstract = "The inhibition of SARS-Cov-2 S binding with hACE2, expressed in most human tissues, may prevent the severity of virus infection. However, commercial ACE2 inhibitor drugs are still limited, while several natural compounds have already been reported to have anti-ACE2 activity. We found the potential of hydrolyzed glucomannan of porang tuber in the inhabitation of binding activity between ACE2 and S1 of SARS-Cov-2.",

keywords = "ACE2, Glucomannan, Porang, S1, SARS-Cov-2",

author = "Ulayya, \{Amira Hasnanuha\} and Mubarok, \{Ahmad Zaki\} and Widodo Widodo and Widjanarko, \{Simon Bambang\} and Marlita Marlita",

note = "Publisher Copyright: {\textcopyright} 2022 by Author/s and Licensed by Modestum.",

year = "2022",

month = feb,

doi = "10.29333/ejgm/11402",

language = "English",

volume = "19",

journal = "Electronic Journal of General Medicine",

issn = "2516-3507",

publisher = "Modestum LTD",

number = "1",

}

TY - JOUR

T1 - The Importance of Natural ACE2 Inhibitor

T2 - Potency of Porang (Amorphophallus muelleri) Glucomannan as Anti-SARS-Cov-2

AU - Ulayya, Amira Hasnanuha

AU - Mubarok, Ahmad Zaki

AU - Widodo, Widodo

AU - Widjanarko, Simon Bambang

AU - Marlita, Marlita

PY - 2022/2

Y1 - 2022/2

N2 - The inhibition of SARS-Cov-2 S binding with hACE2, expressed in most human tissues, may prevent the severity of virus infection. However, commercial ACE2 inhibitor drugs are still limited, while several natural compounds have already been reported to have anti-ACE2 activity. We found the potential of hydrolyzed glucomannan of porang tuber in the inhabitation of binding activity between ACE2 and S1 of SARS-Cov-2.

AB - The inhibition of SARS-Cov-2 S binding with hACE2, expressed in most human tissues, may prevent the severity of virus infection. However, commercial ACE2 inhibitor drugs are still limited, while several natural compounds have already been reported to have anti-ACE2 activity. We found the potential of hydrolyzed glucomannan of porang tuber in the inhabitation of binding activity between ACE2 and S1 of SARS-Cov-2.

KW - ACE2

KW - Glucomannan

KW - Porang

KW - S1

KW - SARS-Cov-2

UR - https://www.scopus.com/pages/publications/85126523007

U2 - 10.29333/ejgm/11402

DO - 10.29333/ejgm/11402

M3 - Article

AN - SCOPUS:85126523007

SN - 2516-3507

VL - 19

JO - Electronic Journal of General Medicine

JF - Electronic Journal of General Medicine

IS - 1

M1 - em340

ER -

The Importance of Natural ACE2 Inhibitor: Potency of Porang (Amorphophallus muelleri) Glucomannan as Anti-SARS-Cov-2

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this