The Diagnostic Value of Platelet Count and MPV in Suspected COVID-19 Patient at Dr. Saiful Anwar Hospital

COVID-19 is a disease caused by SARS-CoV-2. Hematology alterations like lymphopenia are common, but study on platelet remains limited. The incidence of thrombocytopenia in COVID-19 patients is 5-53.6%. This study aimed to analyze the diagnostic value of platelet count and MPV in COVID-19. A study with a cross-sectional design took place at Dr. Saiful Anwar Hospital between March and June 2020. Data were collected at first admission. SARS-CoV-2 gene detection with the RT-PCR method was used in this study as a confirmatory test. A total of 115 patients suspected of COVID-19 were involved at the end of the study with 69 positive and 46 negative results. AUROC for platelet was 0.336 (CI: 95%, 0.238–0.435, p=0.01); MPV was 0.488 (CI 95%, 0.378–0.598, p=0.762). Platelet count and MPV did not have good diagnostic values for COVID-19. This might be due to different conditions that the patient might have at admission. Thrombocytopenia and increased MPV are often caused by the hyperinflammatory condition and severe infection as mentioned in another study. Platelet count and MPV alone can't be used to diagnose COVID-19. Coincide use of another marker such as inflammatory markers might be useful. Future studies with larger samples and serial testing may be needed to further evaluate the diagnostic value of platelet count and MPV.