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Solvent effect on morphology of polystyrene coating and their role to improvement for biomolecule immobilization in application of QCM based biosensor

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

This research is focused on the synthesis of a polystiren layer for biosensors based on a Quartz Crystal Microbalance sensor (QCM) to immobilize the biomolecule. The polystyrene thin film was deposited by means of spin coating method with various solvents, such as chloroform, toluene, xylene, and tetrahydrofuran (THF), containing a 3% polystyrene solution by mass. The morphologies of the polystyrene layers were observed via SEM/EDx. The polystyrene surface coated using chloroform as the solvent has a rougher morphology and the largest diameter pores compared with the other solvents. The result show the polystyrene surface coating produced with chloroform caused a higher frequency change, which resulted in the binding of a wider range of biomolecules.

Original languageEnglish
Title of host publicationAdvances in Measurements and Information Technologies
PublisherTrans Tech Publications
Pages54-57
Number of pages4
ISBN (Print)9783038350392
DOIs
Publication statusPublished - 2014
Event2014 International Conference on Sensors Instrument and Information Technology, ICSIIT 2014 - Guangzhou, China
Duration: 18 Jan 2014 → 19 Jan 2014

Publication series

NameApplied Mechanics and Materials
Volume530-531
ISSN (Print)1660-9336
ISSN (Electronic)1662-7482

Conference

Conference2014 International Conference on Sensors Instrument and Information Technology, ICSIIT 2014
Country/TerritoryChina
CityGuangzhou
Period18/01/14 → 19/01/14

Keywords

  • Immobilization
  • Polystirene
  • QCM
  • Solvents
  • Surface morphology

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