TY - JOUR
T1 - Profile of pituitary adenoma in patients from rural areas
T2 - A study at Dr. Saiful Anwar hospital, Indonesia, 2024
AU - Wardhana, Donny Wisnu
AU - Balafif, Farhad
AU - Nazwar, Tommy Alfandy
AU - Balafif, Fachriy
AU - Vierlia, Wino Vrieda
AU - Maharani, Iriana
AU - Rosandi, Rulli
AU - Sasiarini, Laksmi
AU - Rahmawati, Dessika
AU - Yueniwati, Yuyun
AU - Tjahjono, Harjoedi Adji
AU - Kholipah, Anisa Nur
N1 - Publisher Copyright:
© 2025 Published by Scientific Scholar on behalf of Surgical Neurology International. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
PY - 2025
Y1 - 2025
N2 - Background: Pituitary adenoma is a benign tumor that can greatly affect prognosis, with delayed diagnosis posing a significant challenge. In Indonesia, epidemiological data on this tumor remain scarce. This study aims to explore the clinical profile of pituitary adenoma patients treated at Dr. Saiful Anwar General Hospital in 2024. Methods: A retrospective, single-center, consecutive case series study was conducted by a multidisciplinary research team. Diagnoses were pathologically confirmed through clinical and radiological assessments. Inclusion criteria were patients diagnosed and operated on in 2024. Patients with incomplete data were included in the descriptive analysis but excluded from specific analyses. Results: In 2024, 17 pituitary adenoma patients were treated at Dr. Saiful Anwar General Hospital. The majority were female (70.58%) and aged ≥18 years (100%). Visual disturbance was the predominant presenting symptom (88.23%). The most common tumor type was functional adenoma (prolactinoma, 52.94%), with Knosp grades 3A and 4 each found in 29.42% and 23.53% of cases. All patients underwent endonasal transsphenoidal surgery, with the majority achieving near-total resection (47.05%). Postoperatively, patients demonstrated favorable outcomes: All were discharged alive (100%), had normal urinary function at discharge (100%), and experienced improvements in hormonal status (77.77%), visual acuity (93.33%), and olfaction (100%). Conclusion: The endonasal transsphenoidal approach is a safe and effective technique for pituitary adenoma management. Multidisciplinary collaboration and integrated care improve outcomes and postoperative monitoring. Strengthening rural referral systems and implementing telemedicine may enhance access and longterm follow-up.
AB - Background: Pituitary adenoma is a benign tumor that can greatly affect prognosis, with delayed diagnosis posing a significant challenge. In Indonesia, epidemiological data on this tumor remain scarce. This study aims to explore the clinical profile of pituitary adenoma patients treated at Dr. Saiful Anwar General Hospital in 2024. Methods: A retrospective, single-center, consecutive case series study was conducted by a multidisciplinary research team. Diagnoses were pathologically confirmed through clinical and radiological assessments. Inclusion criteria were patients diagnosed and operated on in 2024. Patients with incomplete data were included in the descriptive analysis but excluded from specific analyses. Results: In 2024, 17 pituitary adenoma patients were treated at Dr. Saiful Anwar General Hospital. The majority were female (70.58%) and aged ≥18 years (100%). Visual disturbance was the predominant presenting symptom (88.23%). The most common tumor type was functional adenoma (prolactinoma, 52.94%), with Knosp grades 3A and 4 each found in 29.42% and 23.53% of cases. All patients underwent endonasal transsphenoidal surgery, with the majority achieving near-total resection (47.05%). Postoperatively, patients demonstrated favorable outcomes: All were discharged alive (100%), had normal urinary function at discharge (100%), and experienced improvements in hormonal status (77.77%), visual acuity (93.33%), and olfaction (100%). Conclusion: The endonasal transsphenoidal approach is a safe and effective technique for pituitary adenoma management. Multidisciplinary collaboration and integrated care improve outcomes and postoperative monitoring. Strengthening rural referral systems and implementing telemedicine may enhance access and longterm follow-up.
KW - Endonasal transsphenoidal surgery
KW - Indonesia
KW - Patient profile
KW - Pituitary adenoma
UR - https://www.scopus.com/pages/publications/105016883551
U2 - 10.25259/SNI_516_2025
DO - 10.25259/SNI_516_2025
M3 - Article
AN - SCOPUS:105016883551
SN - 2229-5097
VL - 16
JO - Surgical Neurology International
JF - Surgical Neurology International
M1 - 374
ER -