Larvae of hermetia illucens promotes the immunocompetence of haematology and muscle histopatology of common carp (Cyprinus carpio) challenged with aeromonas hydrophila

Immunostimulant of Hermetia illucens larvae was prepared for assessment on total leukocyte, differential of leukocyte and muscle histopathology of common carp. The extract of Hermetia illucens larvae was administrated in the diet at A (4%), B (6%), C (8%), and D (10%). The extract of Hermetia illucens larvae contained of flavonoid compounds, tannins/polyphenols and alkaloids. During 30 days of the feeding trial, total leukocyte was decreased as well as decreament of differential of leukocyte at dose C (8%) also at that dose was showed the best increament of immune system of Cyprinus carpio, average of total leukocyte post-infection results was shown 1,95 x 10⁵ sel/ml and differential of leukocyte (lymphocytes, monocytes, neutrophils) was shown 81,55%; 16,42%; 0.33%. Furthermore, the histopathological of muscle before being fed the extract showed the oedema, vacuolisation, and necrosis. The average score of the lowest muscle damage was also shown 1.27%; 1.47%; and 1.4% at dose C (8%).