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Immunoenhancing effect of Lactobacillus Reuteri on immunized mice intestine using Cholerae Toxin Subtype B

  • Musjaya Guli
  • , Oski Illiandri
  • , Sri Winarsih
  • , Wisnu Barlianto
  • , Sumarno Reto Prawiro*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The immunoenhancing effects of probiotic Lactobacillus reuteri have assessed via mouse intragastric inoculation. The number of immunoglobulin A-positive cells, cathelicidin, and beta-defensin in the small intestine in response to adhesion molecule stimulation (CTB v cholera) increased in mice fed L. reuteri. Intestine mass also decreased in the small intestine of mice fed Lactobacillus reuteri. No differences were found in body weight, food intake, and clinical signs between mice fed Lactobacillus reuteri and the control group. Results indicated that Lactobacillus reuteri is a probiotic with immunoenhancing properties via IgA and beta-defensins and cathelicidin.

Original languageEnglish
Pages (from-to)11-17
Number of pages7
JournalJournal of Advanced Pharmacy Education and Research
Volume11
Issue number1
DOIs
Publication statusPublished - 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • beta-defensin
  • cathelicidin
  • IgA
  • lactobacillus reuteri
  • probiotic

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