Correlation Between NT pro-BNP, Troponin I and Inhospital Mortality in Miokard Akut Patients Who Have Already Undergone Percutaneous Coronary Intervention: a Report from ONE ACS Registry Subarea dr. Saiful Anwar Malang Hospital

Background: Many research have looked into the potential of various biomarkers as predictors of intrahospital mortality in patients with STEMI. Patients with a history of heart failure, patients with STEMI with cardiogenic shock, and patients with heart failure all had a similar association between pro-BNP NT and intra-hospital mortality. In STEMI patients, troponin is another biomarker that can be utilized to predict intrahospital mortality with NT pro BNP. Objectives: To determine the correlation between NT pro BNP and troponin I and intrahospital mortality in STEMI patients who had had PCI at RSUD dr. Saiful Anwar Malang. Methods: A retrospective cohort research with an observational analysis design, targeted 391 STEMI patients who underwent PCI at RSUD dr. Saiful Anwar Malang between January 2018 and August 2022 Result: With AUC NT pro BNP 0.840 (95% confidence interval [CI]: 0.789 – 0.892) and troponin I AUC 0.818 (95% CI: 0.753 – 0.882), the ROC curve demonstrated a high degree of discriminating. It was determined that there was a strong correlation between NT pro BNP and intrahospital mortality in AMI EST patients who had had PCI, with a R value of 0.70; OR 10,484 (95% confidence interval [CI]: 7,731–19,366). With a R value of 0.4, there was a moderate connection between troponin I and intrahospital mortality in STEMI patients who had had PCI; the odds ratio was 6,167 (95% confidence interval: 2,286–16,637). Conclusion: There were a strong and moderate correlation between NT pro BNP and troponin I, respectively, with inhospital mortality in STEMI patient.