Combination of 1064-nm QS:Nd-YAG laser with modified Jessner's peel and dermal fibroblast conditioned medium serum for the treatment of post inflammatory hyperpigmentation on lower limb

Post-inflammatory hyperpigmentation (PIH) has clinical manifestations in the form of macules or patches with the same distribution and location where the inflammatory process begins. This condition can occur in any part of the body, including the lower extremities. Combination therapy is considered more than single therapy. We reported a case of PIH on lower limbs of 26 year old male Fitzpatrick IV. After 1 month of using the topical therapy, the patient was programmed for the 1064-nm QS:Nd-YAG Laser combination followed by Modified Jessner chemical peel in the same session 6 times with 1 month intervals. After the procedure, the treated area is applied with a serum containing DFCM. After 6 therapy sessions, HPI faded. This combination gave satisfactory results in cases of HPI lower limbs on Fitzpatrick skin type IV.