Antibacterial candidate of chaetoceros calcitrans against aeromonas salmonicida bacteria based in vitro

Fish disease is an adverse thing in aquaculture’s activities. One of the most harmful fish diseases is the bacterial infection of Aeromonas salmonicida. This bacterium can cause furunculosis. Control of bacterial diseases usually uses antibiotics, therefore we need another alternative, namely to use antibacterial from Chaetoceros calcitrans.The results showed that this chateoceros has antibacterial namely terpenoids. MIC results showed that with a dose of 0.1 ppm chaetoceros extract was able to inhibit bacterial growth. From the results the disc diffusion test showed 45.3 ppm has the largest inhibitory zone against A. salmonicida with an average of 11.4 mm which is included in the strong category.