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Antibacterial activities of β-glucan (laminaran) against gram-negative and gram-positive bacteria

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

This study aimed to determine the antibacterial activity of β-Glucan (laminaran) of LAE and LME extracts from brown algae Sargassum crassifolium using HPMS and Ultrasonication against Gram-positive bacteria (Bacillus subtilis and Staphylococcus aureus) and Gram-negative bacteria (Salmonella typhimurium and Escherichia coli). The highest antibacterial activities of LME extract obtained using the HPMS method against Gram-positive bacteria (B. subtilis and S. aureus) were at 18:10 and 18.80 mm. The ultrasonication method showed a lower inhibition trend than the HPMS method, with MIC and MBC values of 250 mg/ml and 2-8 CFU/ml, respectively, in all Gram-negative and Gram-positive bacteria. The results showed that LME extract at a concentration of 250 mg/mL is bacteriostatic against Gram-positive and -negative bacteria.

Original languageEnglish
Title of host publication7th International Conference on Global Resource Conservation
Subtitle of host publicationFrom Traditional Herbal Medicine into Synthetic Biology for Better Human Lives
EditorsIrfan Mustafa, Bhupal Govinda Shrestha, Nazefah Abdul Hamid
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735415164
DOIs
Publication statusPublished - 17 May 2017
Event7th International Conference on Global Resource Conservation: From Traditional Herbal Medicine into Synthetic Biology for Better Human Lives, ICGRC 2016 - East Java, Indonesia
Duration: 2 Nov 20164 Nov 2016

Publication series

NameAIP Conference Proceedings
Volume1844
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference7th International Conference on Global Resource Conservation: From Traditional Herbal Medicine into Synthetic Biology for Better Human Lives, ICGRC 2016
Country/TerritoryIndonesia
CityEast Java
Period2/11/164/11/16

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