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A new havanensin-type limonoid from Chisocheton macrophyllus

  • Nurlelasari
  • , Intan Rahmayanti
  • , Supriatno Salam
  • , Agus Safari
  • , Desi Harneti
  • , Rani Maharani
  • , Ace Tatang Hidayat
  • , Mulyadi Tanjung
  • , Rurini Retnowati
  • , Yoshihito Shiono
  • , Unang Supratman*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A new havanensin-type limonoid, 16β-hydroxydysobinin (1), along with four known limonoids (2–5), have been isolated from the seeds of Chisocheton macrophyllus. The chemical structure of the new compound was determined by referencing spectroscopic data, and by comparison to those related spectra previously reported. Each compound was evaluated for their cytotoxic effects against Michigan Cancer Foundation-7 (MCF-7) breast cancer cells and display no significant activity.

Original languageEnglish
Article number35
JournalApplied Biological Chemistry
Volume64
Issue number1
DOIs
Publication statusPublished - Dec 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • 16β-hydroxydysobinin
  • Chisocheton macrophyllus
  • Limonoid
  • MCF-7
  • Meliaceae

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